In 19 BBY, during the Battle of Ringo Vinda, she and Tiplar led her forces in an attack on a Separatist manned space station in the planet's orbit. Although they were outmanned, they fought on to bloody stalemate, until the arrival of the 501st turned the tide - just not in the way they had intended.
As they battled Admiral Trench's forces, Clone Trooper-5385 turned on the Jedi, shooting Tiplar dead. Rushing to her sisters side, the droid reinforcements marched onto their position, forcing the G.A.R to retreat.
Mourning her sister's death, the furious Jedi went to visit the rogue trooper in Anakin Skywalker's custody, demanding answers as to why he had turned on them. However, as Tupp was still under the effect of Executive Order 66, he tried to kill her.
Pinning her assailant against the wall, Tiplee relented from hurting him any further.
Back on Kamino, while discussing Tiplar's murder, she speculated that the Separatists had developed an anti-clone virus.